Cross-sectional imaging of amyloidosis: an organ system-based approach

Systemic amyloidosis--whether primary or secondary--can involve any organ or organ system and imparts significant morbidity and mortality. Unfortunately, imaging findings are only rarely specific, manifesting in a variety of ways (e.g., mass-like lesions, micronodular or diffusely infiltrative process). Sensitivity can be improved by being familiar with these varied image manifestations of amyloidosis and aware of the patient's medical history, because there is a significant association between this and other systemic diseases.