Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hippuric acid in urine: reference values.

Maria Elisa P B Siqueira1, Maria José N Paiva

  • 1Departamento de Análises Clínicas e Toxicológicas, Escola de Farmácia e Odontologia de Alfenas, Alfenas, MG, Brasil. marelisa@int.efoa.br

Revista De Saude Publica
|December 19, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

An Exploratory Study of the Metabolite Profiling from Pesticides Exposed Workers.

Metabolites·2023
Same author

Metabolomic Study of Urine from Workers Exposed to Low Concentrations of Benzene by UHPLC-ESI-QToF-MS Reveals Potential Biomarkers Associated with Oxidative Stress and Genotoxicity.

Metabolites·2022
Same author

Environmental Assessment and Evaluation of Oxidative Stress and Genotoxicity Biomarkers Related to Chronic Occupational Exposure to Benzene.

International journal of environmental research and public health·2019
Same author

A Simple and Quick Method for the Determination of Pesticides in Environmental Water by HF-LPME-GC/MS.

Journal of analytical methods in chemistry·2016
Same author

Determination of 2,5-hexanedione in urine by headspace solid-phase microextraction and gas chromatography.

Journal of analytical toxicology·2009

This study establishes reference values for hippuric acid (HA) in urine for non-toluene-exposed individuals. Age and gender significantly influence HA levels, aiding biomonitoring of toluene-exposed workers.

Area of Science:

  • Environmental Health
  • Toxicology
  • Biomonitoring

Background:

  • Hippuric acid (HA) is a metabolite used in biomonitoring.
  • Establishing reference values is crucial for interpreting exposure levels.
  • Toluene exposure can impact HA levels, necessitating population-specific data.

Purpose of the Study:

  • To determine reference values for urinary hippuric acid (HA) in a healthy Brazilian population.
  • To investigate the influence of age, gender, alcohol, and tobacco on HA levels.
  • To provide data for biomonitoring programs for toluene-exposed workers.

Main Methods:

  • 115 healthy, toluene-nonexposed volunteers from Southeastern Brazil participated.
  • Urine samples were analyzed for hippuric acid (HA) and creatinine.

Related Experiment Videos

  • A questionnaire collected data on personal habits and demographics; biochemical tests confirmed health status.

    • Main Results:

    • Reference values for urinary HA were established (mean ± SD: 0.18 ± 0.10 g HA/g creatinine).
    • Significant differences in HA levels were observed between genders and age groups (p<0.05).
    • Alcohol consumption and smoking did not significantly alter urinary HA levels.

    Conclusions:

    • The established reference values for urinary HA are applicable for biomonitoring toluene-exposed workers.
    • Age and gender are significant factors influencing hippuric acid (HA) reference values.
    • These findings are particularly relevant for the southern region of Minas Gerais, Brazil.