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Published on: August 25, 2014
[A sixteen-year epidemiological profile of a pediatric intensive care unit, Brazil]
Paulo Roberto Einloft1, Pedro Celiny Garcia, Jefferson Pedro Piva
1Serviço de Terapia Intensiva e Emergência, Hospital São Lucas, Faculdade de Medicina, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS, Brasil.
Insights
Pediatric Intensive Care Unit (PICU) data reveal higher mortality rates in malnourished children under 12 months. Sepsis is the primary cause of death in this vulnerable pediatric population.
Area of Science:
- Pediatric critical care medicine
- Epidemiology
- Public health
Context:
- A retrospective analysis of patients admitted to a Brazilian Pediatric Intensive Care Unit (PICU) between 1978 and 1994.
- The study aimed to understand the epidemiological profile of critically ill children and identify factors associated with mortality.
Purpose:
- To review epidemiological data of patients admitted to a PICU in Brazil.
- To compare medical aspects related to disease severity and mortality.
- To profile patients, including demographics, disease prevalence, and mortality rates.
Summary:
- A total of 13,101 patients were analyzed. The majority were male (58.4%), under 12 months old (40.4%), well-nourished (69.5%), and had clinical disease (73.1%).
- The overall mortality rate was 7.4%. Infants under 12 months had a relative risk (RR) of 1.86 for mortality, and malnutrition showed an RR of 2.98.
- Sepsis was identified as the leading cause of death.
Impact:
- Highlights the critical impact of malnutrition and young age on pediatric mortality in intensive care settings.
- Provides essential data for targeted interventions and resource allocation in pediatric critical care in Brazil.
- Informs public health strategies aimed at improving nutritional status and reducing sepsis-related deaths in young children.
Objective:
To review epidemiological data from patients admitted to a Pediatric Intensive Care Unit (PICU), Brazil, and to compare them to medical aspects associated to disease severity and mortality. Also, to profile these patients, including demographic data, disease prevalence, mortality rates and associated factors.
Methods:
Retrospective data were collected from all patients admitted in a PICU of a university hospital between 1978 and 1994. Data were presented as percentages and compared using Chi-square, and calculating the relative risk (RR) with a 95% confidence interval, p<0.05.
Results:
Of 13, 101 patients selected, most of them were boys (58.4%), younger than 12 months of age (40.4%), well-nourished (69.5%), and with clinical disease (73.1%). The general mortality rate was 7.4%. Patients aged less than 12 months showed a RR of 1.86 (CI 1.65 - 2.10; p<0.0001), while the RR of malnutrition was 2.98 (CI 2.64 - 3.36; p<0.0001).
Conclusions:
The epidemiological survey showed that the mortality is higher in malnourished children younger than 12 months of age. Sepsis was the most main cause of death.
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