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Related Experiment Videos

The expiration reflex in the mouse.

J Korpás, G Kalocsayová

    Physiologia Bohemoslovaca
    |January 1, 1975
    PubMed
    Summary

    The expiration reflex is more easily triggered from the mouth than the trachea in mice. Respiratory tract mechanoreceptors showed low sensitivity to mechanical stimulation.

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    Area of Science:

    • Respiratory Physiology
    • Neuroscience
    • Animal Models

    Background:

    • The respiratory system exhibits complex reflexes in response to mechanical stimuli.
    • Understanding airway mechanoreceptor sensitivity is crucial for respiratory health.
    • The expiration reflex's elicitability varies depending on the stimulation site.

    Purpose of the Study:

    • To investigate the elicitability of the expiration reflex from different airway locations.
    • To assess the mechanoreceptive sensitivity of the respiratory tract mucosa.
    • To identify other prominent respiratory reflexes induced by mechanical stimulation.

    Main Methods:

    • Studied 35 anesthetized albino mice.
    • Mechanically stimulated the oral and tracheal ends of the respiratory tract.
    • Observed and recorded respiratory reflexes and mechanoreceptor responses.

    Main Results:

    • The expiration reflex was elicited from both oral and tracheal sites.
    • Expiration reflex intensity was significantly higher when elicited from the oral end.
    • Sneeze and aspiration reflexes were also observed.
    • Tracheal and bronchial mechanoreceptors demonstrated low sensitivity, often resulting in minimal or no response.

    Conclusions:

    • The oral route is a more potent trigger for the expiration reflex in mice compared to the tracheal route.
    • Respiratory tract mechanoreceptors are generally less sensitive to direct mechanical stimulation.
    • Mechanical airway stimulation can evoke various reflexes, including sneeze and aspiration, alongside the expiration reflex.

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