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Eosinophilic diseases in two Cavalier King Charles spaniels
A J German1, D J Holden, E J Hall
1Department of Clinical Veterinary Science, University of Bristol, Langford House, Bristol BS40 5DU.
The Journal of Small Animal Practice
|December 20, 2002
Summary
Two Cavalier King Charles spaniels developed eosinophilic diseases, including bronchopneumonopathy and enteritis, along with stomatitis. Both cases responded well to glucocorticoid therapy, suggesting a breed predisposition to these eosinophilic syndromes.
Area of Science:
- Veterinary Medicine
- Canine Pathology
- Immunology
Background:
- Eosinophilic diseases are increasingly recognized in veterinary medicine.
- Cavalier King Charles spaniels may have unique predispositions to certain conditions.
- Understanding concurrent conditions is crucial for effective treatment.
Observation:
- Two Cavalier King Charles spaniels presented with distinct clinical signs.
- One dog exhibited dyspnoea and cough (eosinophilic bronchopneumonopathy).
- The second dog presented with gastrointestinal signs (eosinophilic enteritis).
Findings:
- Both dogs concurrently had eosinophilic stomatitis.
- Both systemic eosinophilic conditions and stomatitis responded to immunosuppressive glucocorticoid therapy.
- This is the first report of concurrent eosinophilic stomatitis and systemic eosinophilic disease in this breed.
Implications:
- Cavalier King Charles spaniels may be predisposed to a spectrum of eosinophilic syndromes.
- Early recognition and treatment of eosinophilic stomatitis alongside systemic disease are important.
- Further research into breed-specific immune-mediated diseases is warranted.
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