Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Intrinsic processing in the mammalian superior colliculus.

Tadashi Isa1

  • 1Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji, Okazaki 444-8585, Japan. tisa@nips.ac.jp

Current Opinion in Neurobiology
|December 20, 2002
PubMed
Summary

Direct visual input to the deeper superior colliculus layers can trigger rapid eye movements. This pathway may enable

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sensorimotor Network Alterations and Compensation in Cervical Spondylotic Myelopathy: A 7 T Task-Based and Resting-State Functional MRI Study.

Neurosurgery·2026
Same author

Enhanced sensorimotor cortex responsiveness to nonplegic hand stimulation and motor network assembly during recovery after spinal cord injury in primates.

Scientific reports·2026
Same author

Biological validation of mathematically derived hypothesis in neuroscience.

Current opinion in neurobiology·2026
Same author

Evaluation of a commercial AI-assisted cell counting software for dopaminergic neurons across species.

PloS one·2026
Same author

Addiction-related problems in Japan: A regional perspective.

Addiction (Abingdon, England)·2025
Same author

Synaptic Silencing with Transactivation of Tetanus Neurotoxin for Pathway-Selective Manipulation.

Methods in molecular biology (Clifton, N.J.)·2025

Area of Science:

  • Neuroscience
  • Ophthalmology
  • Motor Control

Background:

  • The superior colliculus integrates visual information and motor commands.
  • Superficial layers receive visual input; deeper layers generate motor output.
  • Inter-layer connections are known but their functional significance is unclear.

Purpose of the Study:

  • To investigate the role of direct visual input to deeper superior colliculus layers.
  • To explore the potential for rapid eye movement generation via this pathway.

Main Methods:

  • Electrophysiological recordings in behaving animals.
  • Stimulation of superficial superior colliculus layers.
  • Analysis of neuronal activity in deeper layers.

Main Results:

  • Direct visual input to superficial layers can induce burst discharges in deeper layer neurons.
  • This neuronal activity correlates with the initiation of saccadic eye movements.
  • These saccades exhibit extremely short reaction times, termed 'express' saccades.

Conclusions:

  • A functional pathway exists for rapid visual-motor transformation in the superior colliculus.
  • This pathway facilitates the generation of 'express' saccadic eye movements.
  • Understanding this circuit may offer insights into visual attention and reaction time.

Related Experiment Videos