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Related Concept Videos

Peptic Ulcer01:27

Peptic Ulcer

Peptic ulcers are erosive lesions of the gastric or duodenal lining, most commonly caused by Helicobacter pylori infection. This Gram-negative, helical bacterium has adapted to survive the stomach’s acidic environment by producing urease, which converts urea into ammonia and carbon dioxide. The ammonia neutralizes gastric acid in the bacterium’s immediate environment, allowing colonization of the gastric mucosa. H. pylori attaches to mucus-secreting epithelial cells, penetrates the mucus...
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Gastritis II: Pathophysiology

The pathophysiology of gastritis begins with the colonization of the stomach lining by Helicobacter pylori (H. pylori). This bacterium spreads mainly via the oral-oral route through saliva or shared utensils, and can also be transmitted in overcrowded or unhygienic environments through contaminated water, despite its brief survival outside the body.ColonizationOnce ingested, H. pylori enters the stomach and begins colonization by navigating through the mucus layer lining the stomach wall. It...
Pyloric Obstruction01:11

Pyloric Obstruction

Pyloric obstruction, also referred to as gastric outlet obstruction, is a condition characterized by narrowing or blockage at the pylorus—the muscular valve regulating the flow of stomach contents into the duodenum. When this passage becomes impaired, the stomach cannot effectively empty its contents into the small intestine. This disruption leads to a range of gastrointestinal symptoms, including early satiety, bloating, epigastric pain, postprandial nausea, persistent vomiting, and...

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Updated: Jul 12, 2026

Intraoperative Gastroscopy for Tumor Localization in Laparoscopic Surgery for Gastric Adenocarcinoma
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Published on: August 9, 2016

Primary gastric adenocarcinoma in a 2.5-year-old girl.

Ali Ihsan Dokucu1, Hayrettin Oztürk, Nihal Kilinç

  • 1Dicle University, Medical School, Department of Pediatric Surgery, 21280 Diyarbakir, Turkey.

Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association
|December 20, 2002
PubMed
Summary

Pediatric gastric adenocarcinoma, a rare cancer, was observed in a 2.5-year-old girl. Despite treatment, the rare childhood cancer proved fatal, highlighting challenges in pediatric oncology.

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Area of Science:

  • Pediatric Oncology
  • Gastrointestinal Pathology

Background:

  • Primary gastric adenocarcinoma is exceptionally rare in pediatric populations.
  • Early-onset cancers present unique diagnostic and therapeutic challenges.

Observation:

  • A case of primary adenocarcinoma of the stomach is presented in a 2.5-year-old female.
  • The tumor was located at the lesser curvature of the stomach.
  • The patient had no family history or identifiable predisposing factors.

Findings:

  • Despite complete surgical resection and chemotherapy, the patient succumbed to the disease.
  • The aggressive nature of this rare pediatric gastric cancer was evident.
  • Tumor recurrence or metastasis likely contributed to the fatal outcome.

Implications:

  • This case underscores the need for increased awareness and research into rare pediatric gastrointestinal malignancies.
  • Further investigation into the etiology and optimal treatment strategies for pediatric gastric adenocarcinoma is warranted.
  • Improved diagnostic tools and targeted therapies may be crucial for improving outcomes in young cancer patients.