Selective serotonin reuptake inhibitor. Discontinuation syndrome
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Updated: Sep 28, 2026

Thermostabilization, Expression, Purification, and Crystallization of the Human Serotonin Transporter Bound to S-citalopram
Published on: November 27, 2016
1Sinclair School of Nursing, University of Missouri, Columbia, MO 65211, USA. finfgeldD@health.missouri.edu
Abstract:
Based on emerging research findings, nurses are urged to become more aware of SSRI discontinuation syndrome. To ameliorate or avoid the associated symptoms, client education is recommended, and dosage tapering is encouraged whenever possible. Although the symptoms associated with discontinuation syndrome usually are mild, they may pose particular safety concerns for clients with co-occurring conditions. In these situations, precautions should be taken to prevent exacerbation of existing problems.
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