Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Strategies for Assessing and Addressing Confounding01:25

Strategies for Assessing and Addressing Confounding

331
Confounding is a critical issue in epidemiological studies, often leading to misleading conclusions about associations between exposures and outcomes. It occurs when the relationship between the exposure and the outcome is mixed with the effects of other factors that influence the outcome. Given that, addressing confounding is of high importance for drawing accurate inferences in research.
Confounding can be addressed at both the design phase of a study and through analytical methods after data...
331
Mechanistic Models: Compartment Models in Individual and Population Analysis01:23

Mechanistic Models: Compartment Models in Individual and Population Analysis

217
Mechanistic models are utilized in individual analysis using single-source data, but imperfections arise due to data collection errors, preventing perfect prediction of observed data. The mathematical equation involves known values (Xi), observed concentrations (Ci), measurement errors (εi), model parameters (ϕj), and the related function (ƒi) for i number of values. Different least-squares metrics quantify differences between predicted and observed values. The ordinary least...
217
Modeling in Therapy01:26

Modeling in Therapy

344
Modeling, a key technique in therapy, uses observational learning to help clients acquire and practice new skills by watching therapists demonstrate desired behaviors. This approach, rooted in Albert Bandura's concept of vicarious learning, plays a significant role in therapeutic interventions for various psychological conditions, including social anxiety, ADHD, and depression.
Participant Modeling
Participant modeling involves therapists demonstrating calm and effective behaviors in...
344
Dose-Response Relationship: Overview01:03

Dose-Response Relationship: Overview

4.6K
Agonists can bind with and activate receptors, resulting in the formation of drug-receptor complexes. Once formed, these complexes catalyze many biochemical processes at the cellular level and subsequently induce a pharmacologic response. The degree of response is directly proportional to the fraction of activated receptors, which in turn, depends on the concentration of the drug at the receptor site as well as the sensitivity of the receptor. An increase in the administered dose contributes to...
4.6K
Response Surface Methodology01:16

Response Surface Methodology

567
Response Surface Methodology (RSM) is a collection of statistical and mathematical techniques used to develop, improve, and optimize processes. It is particularly valuable when many input variables or factors potentially influence a response variable.
The process of RSM involves several key steps:
567
Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving01:29

Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving

249
Mechanistic models play a crucial role in algorithms for numerical problem-solving, particularly in nonlinear mixed effects modeling (NMEM). These models aim to minimize specific objective functions by evaluating various parameter estimates, leading to the development of systematic algorithms. In some cases, linearization techniques approximate the model using linear equations.
In individual population analyses, different algorithms are employed, such as Cauchy's method, which uses a...
249

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Development of a Potent Engineered Microbial Lipase for the Treatment of Exocrine Pancreatic Insufficiency.

Gastro hep advances·2026
Same author

Microbiome Integrity Protects Against Glial-Mediated Tau and Amyloid Pathology Through Circadian and Autophagy Homeostasis.

bioRxiv : the preprint server for biology·2026
Same author

Novel And Efficient Method for Drosophila Heart Fluorescence Staining with Cryosectioning.

Journal of visualized experiments : JoVE·2025
Same author

Seizure freedom and reducing the risk of sudden unexpected death in patients with focal epilepsy treated with cenobamate or other antiseizure medications.

Epilepsia·2025
Same author

Direct Cryosectioning of Drosophila Heads for Enhanced Brain Fluorescence Staining and Immunostaining.

Journal of visualized experiments : JoVE·2025
Same author

Interferometric single-shot parity measurement in InAs-Al hybrid devices.

Nature·2025

Related Experiment Video

Updated: Jan 5, 2026

Author Spotlight: Deciphering the Long-Term Effects of Low-Level Blast Exposures in Mice
06:00

Author Spotlight: Deciphering the Long-Term Effects of Low-Level Blast Exposures in Mice

Published on: May 24, 2024

1.3K

Chapter three: methodology of exposure modeling.

Demetrios J Moschandreas1, John Watson, Peter D'Abreton

  • 1Department of Chemical and Environmental Engineering, llinois Institute of Technology. Chicago, IL 60616-3793, USA. djm@iit.edu

Chemosphere
|December 21, 2002
PubMed
Summary

This chapter reviews exposure assessment methods for Particulate Matter (PM), covering measurement, estimation, and modeling techniques. It evaluates their strengths and limitations for risk assessment and management.

More Related Videos

An Air-liquid Interface Bronchial Epithelial Model for Realistic, Repeated Inhalation Exposure to Airborne Particles for Toxicity Testing
09:29

An Air-liquid Interface Bronchial Epithelial Model for Realistic, Repeated Inhalation Exposure to Airborne Particles for Toxicity Testing

Published on: May 13, 2020

12.3K
A New Portable In Vitro Exposure Cassette for Aerosol Sampling
07:01

A New Portable In Vitro Exposure Cassette for Aerosol Sampling

Published on: February 22, 2019

7.5K

Related Experiment Videos

Last Updated: Jan 5, 2026

Author Spotlight: Deciphering the Long-Term Effects of Low-Level Blast Exposures in Mice
06:00

Author Spotlight: Deciphering the Long-Term Effects of Low-Level Blast Exposures in Mice

Published on: May 24, 2024

1.3K
An Air-liquid Interface Bronchial Epithelial Model for Realistic, Repeated Inhalation Exposure to Airborne Particles for Toxicity Testing
09:29

An Air-liquid Interface Bronchial Epithelial Model for Realistic, Repeated Inhalation Exposure to Airborne Particles for Toxicity Testing

Published on: May 13, 2020

12.3K
A New Portable In Vitro Exposure Cassette for Aerosol Sampling
07:01

A New Portable In Vitro Exposure Cassette for Aerosol Sampling

Published on: February 22, 2019

7.5K

Area of Science:

  • Environmental Health Sciences
  • Epidemiology
  • Toxicology

Background:

  • Exposure assessment is crucial for understanding health risks.
  • Particulate Matter (PM) poses significant public health challenges.
  • Evaluating exposure assessment evolution is key to refining risk analysis.

Purpose of the Study:

  • To introduce and critically evaluate the concept and evolution of exposure assessment for Particulate Matter (PM).
  • To review and assess various exposure measurement, estimation, and modeling methodologies.
  • To discuss the role of exposure assessment in risk assessment and management.

Main Methods:

  • Literature appraisal of exposure assessment concepts and methodologies.
  • Review of exposure measurement and estimation techniques.
  • Evaluation of various exposure modeling approaches (deterministic, regression, stochastic).

Main Results:

  • Multiple exposure assessment methodologies for PM were reviewed and assessed.
  • Estimation methods encompass source evaluation, indoor/outdoor environments, and activity patterns.
  • Fate and transport models, alongside source attribution, were addressed for concentration estimation.

Conclusions:

  • Exposure assessment is an integral component of risk assessment and management.
  • Strengths, limitations, and assumptions of different exposure assessment methods were discussed.
  • The chapter provides a comprehensive overview of PM exposure assessment for informed decision-making.