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Management of acute optic neuritis
S J Hickman1, C M Dalton, D H Miller
1NMR Research Unit, Institute of Neurology, University College London, London, UK.
Lancet (London, England)
|December 21, 2002
Summary
Optic neuritis, a cause of reversible vision loss, can be isolated or linked to multiple sclerosis. Corticosteroids accelerate recovery, but optimal investigation and treatment strategies remain debated.
Area of Science:
- Ophthalmology
- Neurology
Background:
- Optic neuritis causes reversible vision loss and can be an early sign of multiple sclerosis.
- Management strategies for optic neuritis vary, with some aspects remaining controversial.
Purpose of the Study:
- To review diagnostic features and differential diagnoses of optic neuritis.
- To provide practical guidance on managing patients with optic neuritis.
- To discuss the association between optic neuritis and multiple sclerosis risk.
Main Methods:
- Literature review of clinical trials and studies on optic neuritis.
- Analysis of diagnostic criteria and management protocols.
- Evaluation of data on multiple sclerosis risk and disease-modifying treatments.
Main Results:
- Corticosteroid treatment speeds visual recovery in optic neuritis but does not alter the final visual outcome.
- Evidence supports defining multiple sclerosis risk and evaluating disease-modifying drugs for affected individuals.
Conclusions:
- While corticosteroids aid recovery, optimal investigation and treatment timing for optic neuritis require further clarification.
- Understanding the link to multiple sclerosis is crucial for long-term patient management and prognosis.