[Complex of factors affecting heart rate dispersion in survivors of myocardial infarction]

Kardiologiia
|December 21, 2002
PubMed

Insights

Heart rate variability reduction after myocardial infarction is associated with patient age, heart remodeling, and heart failure severity. These factors impact cardiac health in post-MI patients.

Area of Science:

  • Cardiology
  • Clinical Investigation
  • Physiology

Context:

  • Post-myocardial infarction (MI) patients exhibit altered autonomic function.
  • Heart rate variability (HRV) is a key indicator of cardiac autonomic control.
  • Understanding factors influencing HRV is crucial for managing post-MI patients.

Purpose:

  • To identify independent variables associated with heart rate variability parameters in patients with postinfarction cardiosclerosis.
  • To explore the relationship between clinical and instrumental data and HRV in myocardial infarction survivors.

Summary:

  • This study investigated 74 patients 6+ months post-MI, analyzing temporal and spectral HRV from ECGs.
  • Multiple linear regression identified predictors of HRV, including age, cardiac remodeling, and left ventricular dysfunction.
  • Reduced HRV in MI survivors correlates with advanced age, cardiac remodeling, and heart failure severity.

Impact:

  • Provides insights into the multifactorial nature of autonomic dysfunction post-MI.
  • Highlights the importance of assessing cardiac structure and function for HRV evaluation.
  • Informs clinical strategies for risk stratification and management of heart failure in post-MI populations.
Abstract

Related Concept Videos

Factors Influencing Heart Rate01:30

Factors Influencing Heart Rate

The heart rate, or pulse rate, is a vital indicator of cardiovascular health. It reflects the number of times the heart beats per minute. Various physiological and environmental factors influence heart rate, increasing or decreasing cardiac output. Understanding these factors is crucial for assessing heart function and identifying potential health issues.
Let us explore the significant factors affecting heart rate, including age, body temperature, posture, acute pain, chemical influences,...
Pathophysiology of Cardiac Performance01:29

Pathophysiology of Cardiac Performance

Typical heart performance is influenced by heart rate, rhythm, myocardial contraction, and metabolism or blood flow. The cardiac muscle exhibits distinct electrophysiological features, including pacemaker activity and calcium channel control, which play a vital role in the heart's response to various drugs. The autonomic nervous system, comprising the sympathetic and parasympathetic branches, regulates heart rate. Sympathetic activation increases heart rate, while parasympathetic activation...
Pathophysiology of Heart Failure01:17

Pathophysiology of Heart Failure

Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
Cardiac Output I:Effect of Heart Rate on Cardiac Output01:19

Cardiac Output I:Effect of Heart Rate on Cardiac Output

Cardiac Output
Cardiac output (CO) refers to the total amount of blood ejected by one of the ventricles in liters per minute (L/min). In a resting adult, CO ranges from 5 to 6 L/min, adjusting according to the body's metabolic requirements.
Effect of Heart Rate on Cardiac Output
Cardiac output adapts to metabolic demands during stress, physical activity, or illness. The autonomic nervous system regulates heart rate via the sinoatrial node. The parasympathetic nervous system decreases heart rate...
Regulation of Heart Rates01:31

Regulation of Heart Rates

The regulation of heart rate is a complex process controlled by the autonomic nervous system (ANS), hormonal influences, and intrinsic cardiac mechanisms. The ANS has two main components: the sympathetic nervous system (SNS) and the parasympathetic nervous system (PNS).
The SNS increases heart rate through the release of norepinephrine and epinephrine, which act on beta-1 adrenergic receptors in the heart. This action increases the rate of depolarization in the sinoatrial (SA) node, the heart's...
Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...