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Updated: Sep 28, 2026

Orthotopic Hind Limb Transplantation in the Mouse
Published on: February 12, 2016
[Therapy of the peromelic form of symbrachydactyly by double second-toe transplantation]
W Hülsemann1, P Preisser, R Habenicht
1Handchirurgische Abteilung, Katholisches Kinderkrankenhaus Wilhelmstift, Hamburg.
Abstract:
From 1989 to 2001 eleven children with the peromelic type of symbrachydactyly underwent a staged double second toes transplantation for restoration of two finger rays. The second toe of the feet were transplanted first to the small finger position and in the second step to the thumb position. One failure occurred in the first toe transplantation and another developed a venous thrombosis with partial necrosis and eventually a useless ray. Eight children were reviewed retrospectively in a mean follow-up of 5.3 years. The ability to pinch was restored in four children. In all patients without complications the function of the hand improved and the sensitivity was good.

