Two-level proportional hazards models
Related Experiment Video
Updated: Sep 28, 2026

An R-Based Landscape Validation of a Competing Risk Model
Published on: September 16, 2022
Jerry J Maples1, Susan A Murphy, William G Axinn
1The Methodology Center and Department of Statistics, Pennsylvania State University, 326 Thomas Building, University Park, Pennsylvania 16802, USA. maples@stat.psu.edu
Abstract:
We extend the proportional hazards model to a two-level model with a random intercept term and random coefficients. The parameters in the multilevel model are estimated by a combination of EM and Newton-Raphson algorithms. Even for samples of 50 groups, this method produces estimators of the fixed effects coefficients that are approximately unbiased and normally distributed. Two different methods, observed information and profile likelihood information, will be used to estimate the standard errors. This work is motivated by the goal of understanding the determinants of contraceptive use among Nepalese women in the Chitwan Valley Family Study (Axinn, Barber, and Ghimire, 1997). We utilize a two-level hazard model to examine how education and access to education for children covary with the initiation of permanent contraceptive use.
Related Concept Videos
Hazard Rate
Parametric Survival Analysis: Weibull and Exponential Methods
Weibull Distribution
The Weibull distribution is a flexible model used in parametric survival analysis. It can handle both increasing and decreasing hazard rates, depending on its shape parameter...
Hazard Ratio
For example, in a clinical trial evaluating a...
Pharmacodynamic Models: Additive and Proportional Drug Effect Model
Assumptions of Survival Analysis
Comparing the Survival Analysis of Two or More Groups
