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Updated: Sep 28, 2026

Imaging- and Flow Cytometry-based Analysis of Cell Position and the Cell Cycle in 3D Melanoma Spheroids
10:44

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FR-901228 Fujisawa/National Cancer Institute

David M Vigushin1

  • 1Department of Cancer Medicine, MRC Cyclotron Building, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, UK. d.vigushin@ic.ac.uk

Current Opinion in Investigational Drugs (London, England : 2000)
|December 25, 2002
PubMed

Insights

The depsipeptide FR-901228, a histone deacetylase inhibitor, is being developed for cancer treatment. Phase II trials were underway in the US by May 2002.

Area of Science:

  • Oncology
  • Pharmacology

Background:

  • The depsipeptide FR-901228 is a novel histone deacetylase inhibitor.
  • It is being developed as a potential anti-cancer therapeutic agent.

Purpose of the Study:

  • To evaluate the efficacy and safety of FR-901228 in patients with neoplasm.

Main Methods:

  • Phase II clinical trials were initiated in the United States.
  • The study involved patients with various types of neoplasms.

Main Results:

  • The abstract does not contain specific results, but indicates the commencement of Phase II trials.

Conclusions:

  • The development of FR-901228 shows promise as a novel treatment strategy for neoplasms.

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