Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Immunologic changes during minimally invasive surgery.

C A Jacobi1, F Wenger, I Opitz

  • 1Department of Surgery, Humboldt University of Berlin, Charité, Campus Mitte, Schumannstrasse 20/21, D-10117 Berlin, Germany. christoph.jacobi@charite.de

Digestive Surgery
|December 25, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sex-specific efficacy and safety outcomes in patients with resectable stage III non-small-cell lung cancer (NSCLC) undergoing neoadjuvant therapies: a pooled analysis of the SAKK trials 16/96, 16/00, 16/01, 16/08 and 16/14.

ESMO open·2025
Same author

Fluid management of cardiopulmonary bypass during pulmonary endarterectomy for CTEPH patients impacts perioperative outcome.

JHLT open·2025
Same author

Neoadjuvant treatment does not influence PD-L1 expression in stage III non-small-cell lung cancer: a retrospective analysis of tumor samples from the trials SAKK 16/96, 16/00, 16/01, and 16/14.

ESMO open·2023
Same author

Improving the turnaround time of molecular profiling for advanced non-small cell lung cancer: Outcome of a new algorithm integrating multiple approaches.

Pathology, research and practice·2023
Same author

Smoking prevention intervention with school classes in university hospital by thoracic surgeon und pulmonologist. The Zurich prevention project.

Preventive medicine reports·2022
Same author

Corrigendum to 'Long-term outcomes of operable stage III NSCLC in the pre-immunotherapy era: results from a pooled analysis of the SAKK 16/96, SAKK 16/00, SAKK 16/01, and SAKK 16/08 trials': [ESMO Open Volume 7, Issue 2, (2022), 100455].

ESMO open·2022
Same journal

Development of a basic robotic training course for residents in general surgery in the Netherlands.

Digestive surgery·2026
Same journal

Bacterial Colonization in Resected Lymph Nodes During Pancreatic Surgery - A Pilot Study.

Digestive surgery·2026
Same journal

Prognostic Significance of Nutritional and Inflammatory Factors in Gastric Cancer Surgery.

Digestive surgery·2026
Same journal

PIPAC for Malignant Peritoneal Mesothelioma: Current Insights and Future Directions.

Digestive surgery·2026
Same journal

Low Preoperative Haemoglobin Is a Risk Factor for Clavien-Dindo Grade IV-V and Non-Surgical Complications in Colorectal Cancer Surgery.

Digestive surgery·2026
Same journal

Interval Appendicectomy after Conservative Management of Complicated Appendicitis: Balancing Recurrence, Neoplasm Risk, and Surveillance Strategies.

Digestive surgery·2026
See all related articles

Laparoscopic surgery may reduce postoperative inflammation, but the impact of pneumoperitoneum on immune function remains unclear. Further studies are needed to link immune parameter changes to clinical outcomes after minimally invasive surgery.

Area of Science:

  • Immunology
  • Surgical Innovation

Background:

  • Laparoscopic surgery is associated with reduced postoperative inflammation compared to open surgery.
  • The specific impact of pneumoperitoneum on immune defense and function requires further investigation.
  • Current studies often focus on immunologic parameters rather than functional immune responses.

Purpose of the Study:

  • To clarify the influence of pneumoperitoneum on immune defense and function.
  • To bridge the gap between measured immunologic parameters and clinical outcomes.
  • To guide future research on surgical techniques and immune responses.

Main Methods:

  • Review of existing experimental and clinical trials.
  • Analysis of studies measuring immunologic parameters (e.g., cytokines, hormones).

Related Experiment Videos

  • Assessment of studies investigating immunologic functions (e.g., cell activation, proliferation).

    • Main Results:

    • Reduced postoperative inflammation observed with laparoscopic approaches.
    • Unclear influence of pneumoperitoneum on immune defense and function.
    • Lack of demonstrated correlation between immunologic parameter changes and clinical endpoints in current trials.

    Conclusions:

    • Further prospective randomized studies are essential.
    • Investigate both immunologic parameters and functions.
    • Establish clear links between surgical methods and postoperative immune function and clinical outcomes.