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Blood group in otitis media with effusion

Kostas Apostolopoulos1, Ekaterini Labropoulou, Bogris Konstantinos

  • 1Ear, Nose and Throat Department, Faculty of Medicine, University of Athens, Greece. lapa@hol.gr

ORL; Journal for Oto-Rhino-Laryngology and Its Related Specialties
|December 25, 2002
PubMed

Insights

Blood group ABO may influence otitis media with effusion (OME) risk in children. Blood group O appears to offer protection against OME, while blood groups A and B may increase risk.

Area of Science:

  • Pediatrics
  • Immunology
  • Genetics

Background:

  • Otitis media with effusion (OME) is a common childhood condition.
  • The role of host factors, such as blood group, in OME susceptibility is not fully understood.

Purpose of the Study:

  • To investigate the association between ABO blood group system and the risk of developing otitis media with effusion (OME) in children.
  • To determine if Rhesus factor influences OME risk.

Main Methods:

  • A screening program involving 889 children.
  • Evaluations included pneumatic otoscopy, tuning fork tests, audiometry, impedance measures, and ABO blood group testing.
  • Multivariate logistic regression analysis was used to compare OME risk across different blood groups, adjusting for covariates.

Main Results:

  • A statistically significant relationship was found between blood group and OME.
  • Children with blood group O exhibited a significantly lower risk of OME compared to blood group A (reference).
  • Blood group AB showed a non-significant trend towards lower OME risk, while blood group B did not show a reduced risk. Rhesus factor was not associated with OME.

Conclusions:

  • Blood group O (and possibly AB) may confer a protective effect against otitis media with effusion.
  • Blood groups A and B might be associated with an increased burden of OME.
  • ABO blood group is a potential risk factor for OME in children.

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