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[A case of acute hepatitis E].

Nam Jin Kim1, June Sung Lee, Kyung Ah Kim

  • 1Department of Internal Medicine, In-Je University College of Medicine, Ilsan Paik Hospital, Goyang, Korea.

Taehan Kan Hakhoe Chi = the Korean Journal of Hepatology
|December 25, 2002
PubMed
Summary

Hepatitis E virus (HEV) infection, typically found in Asia, has been identified in Korea. This case marks the first report of acute hepatitis E in Korea without a travel history to endemic areas.

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Area of Science:

  • Hepatology
  • Infectious Diseases
  • Virology

Background:

  • Hepatitis E is an acute viral hepatitis with global distribution.
  • Endemic regions include the Indian subcontinent, Southeast Asia, Central Asia, China, the Middle East, Africa, and Mexico.
  • Sporadic cases in non-endemic regions are typically linked to travel history.

Observation:

  • A case of acute icteric hepatitis was observed in Korea.
  • The patient presented with seroconversion of IgM anti-HEV antibodies.
  • Crucially, the patient had no documented travel history to HEV-endemic regions.

Findings:

  • This case represents the first documented instance of acute Hepatitis E infection in Korea.
  • The absence of a travel history suggests potential local transmission or an unrecognized exposure route.

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  • The findings highlight the expanding geographical reach of Hepatitis E virus.

    • Implications:

    • This initial report necessitates increased awareness and surveillance for Hepatitis E in Korea.
    • Further research is required to understand the transmission dynamics and prevalence of HEV in non-endemic regions like Korea.
    • Public health strategies may need to be updated to address potential autochthonous HEV cases.