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Clinical blood flow quantification with segmented k-space magnetic resonance phase velocity mapping
George P Chatzimavroudis1, Haosen Zhang, Sandra S Halliburton
1Section of Cardiovascular Imaging, Division of Radiology, The Cleveland Clinic Foundation, Cleveland, Ohio, USA. g.chatzimavroudis@csuohio.edu
Purpose:
To evaluate the accuracy of segmented k-space magnetic resonance phase velocity mapping (PVM) in quantifying aortic blood flow from through-plane velocity measurements.
Materials And Methods:
Two segmented PVM schemes were evaluated, one with seven lines per segment (seg-7) and one with nine lines per segment (seg-9), in twenty patients with cardiovascular disease. A non-segmented (non-seg) PVM acquisition was also performed to provide the reference data.
Results:
There was agreement between the aortic flow curves acquired with segmented and non-segmented PVM. The calculated systolic and total flow volume per cycle from the seg-7 and the seg-9 scans correlated and agreed with the flow volumes from the non-seg scans (differences < 5%). Sign tests showed that there were no statistically significant differences (P-values > 0.05) between the segmented and the non-segmented PVM measurements [corrected]. Seg-9, which was the fastest among the three sequences, provided adequate spatial and temporal resolution (> 10 phases per cycle).
Conclusion:
Segmented k-space PVM shows great clinical potential in blood flow quantification.