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Related Experiment Videos

[Atrial septal defects: problems in adults].

J Petit1

  • 1Centre chirurgical Marie-Lanne-longue. 133, avenue de la Résistance, 92350 Le Plessis-Robinson.

Archives Des Maladies Du Coeur Et Des Vaisseaux
|December 26, 2002
PubMed
Summary

Clinical features of atrial septal defects in adults have evolved. Closure of atrial septal defects, particularly in older adults, improves symptoms, with percutaneous closure being the preferred method.

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Area of Science:

  • Cardiology
  • Adult Congenital Heart Disease

Background:

  • Clinical presentation of atrial septal defects (ASDs) in adults has shifted due to early surgical interventions and advanced imaging like transesophageal echocardiography.
  • Rare complications of ASDs, including paradoxical embolism and cerebral abscess, are now more accurately diagnosed.
  • Pulmonary hypertension in ASDs is better understood, with severe forms (Eisenmenger's syndrome) being rare and potentially genetic, while less severe forms are common in older adults.

Purpose of the Study:

  • To analyze the changing clinical features of atrial septal defects in adults.
  • To evaluate the long-term benefits and outcomes of atrial septal defect closure in adult populations.
  • To discuss current treatment strategies, including percutaneous closure and surgical intervention.

Main Methods:

  • Review of clinical data and outcomes related to adult patients with atrial septal defects.
  • Analysis of the impact of late closure on symptoms and atrial arrhythmias.
  • Assessment of the role of percutaneous closure versus surgical repair.

Main Results:

  • Late closure of atrial septal defects improves symptoms, though its effect on atrial arrhythmias is limited.
  • Percutaneous closure is the primary treatment modality, with surgery reserved for cases where endovascular methods fail.
  • The indication for closing small atrial septal defects continues to be debated.

Conclusions:

  • The management of atrial septal defects in adults requires consideration of age-related changes and evolving treatment options.
  • Percutaneous closure has become the standard of care for most adult ASDs.
  • Further research is needed to clarify the indications for closure of small atrial septal defects.

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