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Lymphocytic choriomeningitis virus: emerging fetal teratogen
Leslie L Barton1, Marilyn B Mets, Cynthia L Beauchamp
1Department of Pediatrics and Steele Memorial Children's Research Center, University of Arizona, Tucson 85724, USA. llb@peds.arizona.edu
American Journal of Obstetrics and Gynecology
|December 26, 2002
Abstract:
Lymphocytic choriomeningitis virus (LCMV), a rodent-borne arenavirus, is an often undiagnosed human fetal teratogen. We describe a neonate born with hydrocephalus and chorioretinitis after maternal second-trimester symptomatic LCMV infection. Previously reported affected infants are reviewed. We strongly suggest that obstetricians counsel their pregnant patients regarding the potential hazard that contact with infected pet, laboratory, and household mice and hamsters poses to pregnant women and their unborn children.