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Published on: February 17, 2018

[Chronic pericarditis in Hodgkin disease]

Zsófia Miltényi1, Lajos Gergely, Arpád Illés

  • 1Debreceni Egyetem Orvos- és Egészségtudományi Centrum, Altalános Orvostudományi Kar, III. sz. Belgyógyászati Klinika.

Orvosi Hetilap
|December 28, 2002
PubMed

Insights

Late cardiac complications, including chronic constrictive pericarditis, can arise after Hodgkin's disease treatment. Early recognition through patient follow-up is key to managing these rare but serious cardiovascular issues.

Area of Science:

  • Cardiology
  • Oncology
  • Medical Imaging

Background:

  • Cardiovascular complications are significant late sequelae of Hodgkin's disease treatment.
  • Chronic pericardial disease, occurring later than 48 months post-treatment, affects 11-50% of patients with a history of irradiation.

Observation:

  • A case of chronic constrictive pericarditis is presented as a rare late consequence of Hodgkin's disease therapy.
  • A 35-year-old male, treated for Hodgkin's disease with chemotherapy and irradiation, developed pericardial effusion despite remission.
  • Differential diagnoses included radiation-induced pericarditis, hypothyroidism, and primary disease manifestation.

Findings:

  • Histological evaluation confirmed chronic constrictive pericarditis, likely induced by mediastinal irradiation.
  • The patient underwent partial pericardiectomy after repeated pericardial fenestration.
  • Post-surgery, the patient has remained well with no recurrence of pericardial fluid or disease relapse.

Implications:

  • The case highlights the importance of diligent patient follow-up for early detection and management of late treatment complications.
  • Modern radiotherapy techniques may help in avoiding such late-onset cardiovascular complications in Hodgkin's disease patients.
Abstract

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