Related Experiment Video
Updated: Sep 28, 2026

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
Emotional distress and prenatal attachment in pregnancy after perinatal loss
1University of Louisville School of Nursing, Louisville, KY, USA. dsarms01@gwise.louisville.edu
Purpose:
To evaluate the association of previous perinatal loss with parents' levels of depressive symptoms, pregnancy-specific anxiety, and prenatal attachment in a subsequent pregnancy, and to determine whether higher levels of depressive symptoms and pregnancy-specific anxiety were associated with prenatal attachment.
Design:
A three-group comparative design was used to collect cross-sectional survey data. The sample consisted of 103 couples who were in the second trimester of pregnancy: 40 couples who had a perinatal loss in a previous pregnancy, 33 couples were pregnant for the first time, and 30 couples had a history of prior successful pregnancies.
Methods:
Structured questionnaires via in-person or telephone interviews were used to measure depressive symptoms, pregnancy-specific anxiety, and prenatal attachment.
Findings:
Couples with a history of perinatal loss had higher levels of depressive symptoms and pregnancy-specific anxiety than did couples with past successful pregnancies and no losses; mothers had higher levels of symptoms than did fathers in all groups, Couples with and without a history of perinatal loss did not differ in their level of prenatal attachment in the current pregnancy.
Conclusions:
These findings do not support the theory that depressive symptoms and pregnancy-specific anxiety affect subsequent parent-infant attachment in a pregnancy after perinatal loss. However, they do provide insight into the continuing influence of parents' previous loss experience on their depressive symptoms and pregnancy-specific anxiety in subsequent pregnancies. Families should be assessed to examine the potential long-term influence of emotional distress as a result of prior perinatal loss.
Related Concept Videos
Attachment
Attachment Styles
Socioemotional Development during Infancy
Primary Temperament Types
Stella Chess...
Theory of Romantic Attachment in Adulthood
Bonanno's Theory of Grieving
Resilience
The resilience...
Relationship with Parents: Attachment

