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Risk factors for Pseudomonas aeruginosa bacteremia in Thai patients

Krittecho Siripassorn1, Somporn Santiprasitkul, Suthipol Udompanthurak

  • 1Bamrasnaradura Hospital, Department of Communicable Disease Control, Thailand.

Journal of the Medical Association of Thailand = Chotmaihet Thangphaet
|December 28, 2002
PubMed

Insights

This study identified key risk factors for Pseudomonas aeruginosa bacteremia. Hematologic malignancy, hospital-acquired infections, and prior parenteral antibiotic use were significant predictors.

Area of Science:

  • Infectious Diseases
  • Clinical Microbiology
  • Epidemiology

Background:

  • Pseudomonas aeruginosa bacteremia poses a significant threat in hospital settings.
  • Identifying specific risk factors is crucial for effective prevention and treatment strategies.

Purpose of the Study:

  • To determine the independent risk factors associated with Pseudomonas aeruginosa bacteremia.
  • To compare risk factors across different bacteremia types and non-bacteremic controls.

Main Methods:

  • A case-control study design was employed at Siriraj Hospital.
  • Data on demographics, infection types, comorbidities, procedures, and medication use were collected.
  • Univariate and multivariate logistic regression analyses were performed.

Main Results:

  • Univariate analysis indicated associations with hospital-acquired infections, hematologic malignancy, neutropenia, COPD, and antibiotic/cytotoxic agent use.
  • Multivariate analysis identified hematologic malignancy, hospital-acquired infections, and previous parenteral antibiotic use as independent risk factors.

Conclusions:

  • Hematologic malignancy, hospital-acquired infections, and prior parenteral antibiotic use are significant risk factors for P. aeruginosa bacteremia.
  • These findings can inform targeted surveillance and intervention programs to reduce P. aeruginosa bacteremia incidence.

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