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Updated: Jun 24, 2026

Isolation and Biophysical Study of Fruit Cuticles
Published on: March 30, 2012
Supercritical fluid extraction of all-trans-lycopene from tomato
M Salud Gómez-Prieto1, M Mar Caja, Marta Herraiz
1Instituto de Fermentaciones Industriales, CSIC. c/ Juan de la Cierva 3, 28006 Madrid, Spain.
Abstract:
A procedure is proposed for the supercritical fluid extraction of all-trans-lycopene from tomato using carbon dioxide at 40 degrees C without modifier. The present method minimizes the risk of degradation via isomerization and oxidation of health-promoting ingredients, such as lycopene. The effect of different experimental variables on the solvating power of the supercritical fluid was evaluated in terms of both the selectivity achievable in the process and the yield of the extraction of all-trans-lycopene. Satisfactory separations of the all-trans-lycopene isomers from the cis counterparts were achieved using a C(30) column. The obtained extract contained 88% all-trans-lycopene and 12% cis-lycopene.

