Cell-mediated and humoral immune response after lens injury

The authors carried out immunological investigations on lens antigen in 21 injured patients, when only the cornea and the lens were involved. Circulating anti-lens antibodies were found by means of passive haemagglutination technique in 5 out of 16 cases. The cellular immune response was examined in 5 injured patients by the leucocyte migration inhibition test. The cellular immune response to the lens antigen was also demonstrable. The pathogenic role of the humoral and cellular immune response against the 'foreign' antigen was evident.