Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cardiovascular physiology-changes with aging.

Melvin D Cheitlin1

  • 1University of California at San Francisco, Former Chief of Cardiology, San Francisco General Hospital, San Francisco, CA 94110, USA.

The American Journal of Geriatric Cardiology
|December 28, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cardiac auscultation skills among medical trainees.

American heart journal·2025
Same author

Counterintuitive evidence concerning salt and water restriction in acute decompensated heart failure patients: comment on "Aggressive fluid and sodium restriction in acute decompensated heart failure".

JAMA internal medicine·2013
Same author

Sexual activity and cardiovascular disease: a scientific statement from the American Heart Association.

Circulation·2012
Same author

Medical technology--still an adjunct to clinical skills in making a diagnosis: comment on "Utility of clinical examination in the diagnosis of emergency department patients admitted to the department of medicine of an academic hospital".

Archives of internal medicine·2011
Same author

Pulmonary artery rupture from invasive hemodynamic monitoring.

Archives of internal medicine·2011
Same author

Pulmonary artery catheterization in the intensive care unit: just numbers floating by?

Archives of internal medicine·2011
Same journal

Systolic anterior motion of a retained anterior mitral valve leaflet following mitral valve replacement.

The American journal of geriatric cardiology·2008
Same journal

Biomarkers, age, and coronary artery remodeling in patients with acute coronary syndrome.

The American journal of geriatric cardiology·2008
Same journal

Electrocardiographic intervals in the healthy geriatric population--what are the "normals"?

The American journal of geriatric cardiology·2008
Same journal

Coronary events in persons aged 75 years or older in Finland from 1995 to 2002: the FINAMI study.

The American journal of geriatric cardiology·2008
Same journal

Sinus venosus atrial septal defect diagnosed at age 82.

The American journal of geriatric cardiology·2008
Same journal

Frailty, inflammation, and cardiovascular disease: evidence of a connection.

The American journal of geriatric cardiology·2008
See all related articles

Aging causes cardiovascular changes like decreased arterial elasticity and heart rate, leading to conditions such as hypertension and heart failure in older adults.

Area of Science:

  • Cardiovascular Physiology
  • Gerontology
  • Internal Medicine

Background:

  • Cardiovascular system undergoes significant physiological changes with advancing age.
  • These age-related changes must be distinguished from cardiovascular pathologies.
  • Individual aging rates vary, leading to differences between chronological and physiological age.

Purpose of the Study:

  • To delineate the physiological alterations in the cardiovascular system associated with aging.
  • To differentiate normal aging processes from age-related cardiovascular diseases.
  • To understand the implications of these changes for geriatric cardiovascular health.

Main Methods:

  • Review of physiological changes in the cardiovascular system due to aging.
  • Analysis of structural and functional alterations in the heart and vasculature.

Related Experiment Videos

  • Examination of neurohormonal and receptor system modifications with age.

    • Main Results:

    • Aging leads to decreased arterial elasticity and increased stiffness, raising left ventricular afterload and systolic blood pressure.
    • Reduced atrial pacemaker cells decrease intrinsic heart rate; cardiac skeleton fibrosis can cause aortic valve calcification and His bundle damage.
    • Diminished beta-adrenergic responsiveness, baroreceptor/chemoreceptor reactivity, and increased catecholamines are observed.

    Conclusions:

    • Age-associated cardiovascular changes predispose individuals to isolated systolic hypertension, diastolic dysfunction, and heart failure.
    • Atrioventricular conduction defects and aortic valve calcification are common outcomes of the aging cardiovascular system.
    • Understanding these physiological shifts is crucial for managing cardiovascular health in the elderly population.