Related Experiment Video
Updated: Sep 28, 2026

Recurrent Herpetic Stromal Keratitis in Mice, a Model for Studying Human HSK
Published on: December 18, 2012
[Herpetic meningitis in the child]
C Dupuis1, V Despert, P Vigneron
1Département de médecine de l'enfant et de l'adolescent, hôpital Sud, CHU de Rennes, 16, boulevard de Bulgarie, BP 56129, 35056 Rennes, France.
Unlabelled:
In children, viral meningitis is usually caused by Enteroviruses. Herpes simplex viruses (HSV) are known to be a cause of meningo-encephalitis. HSV-2 has been reported to cause recurrent meningitis (Mollaret's meningitis) in adults.
Case Report:
We report the case of a three-year-old girl with HSV-1 meningitis, whose evolution with treatment by aciclovir was good.
Conclusion:
HSV-1 has rarely been reported as a cause of isolated aseptic meningitis in children. Primary phase of herpes simplex virus infection is not usually associated with neurologic complications.
Insights
Herpes simplex virus type 1 (HSV-1) meningitis is rare in children. This case report details a successful treatment of a three-year-old girl with HSV-1 meningitis using aciclovir.
Area of Science:
- Pediatric Neurology
- Infectious Diseases
- Virology
Background:
- Viral meningitis in children is commonly caused by Enteroviruses.
- Herpes simplex viruses (HSV) are recognized causes of meningoencephalitis.
- HSV-2 is associated with recurrent meningitis (Mollaret's meningitis) in adults.
Observation:
- This report details a case of a three-year-old girl diagnosed with HSV-1 meningitis.
- The patient received treatment with the antiviral medication aciclovir.
Findings:
- HSV-1 is an uncommon cause of isolated aseptic meningitis in pediatric populations.
- The patient exhibited a positive clinical response to aciclovir treatment.
Implications:
- This case highlights HSV-1 as a potential, though rare, cause of meningitis in children.
- Early diagnosis and antiviral treatment with aciclovir can lead to favorable outcomes.
- Further research may clarify the role of HSV-1 in pediatric neurological complications.
Related Concept Videos
Bacterial Meningitis I: Introduction
Genital Herpes
Herpes
Chickenpox
Viral Meningitis
Encephalitis l: Introduction