Related Experiment Video
Updated: Aug 11, 2026

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
Published on: February 6, 2019
[Treatment of non-painful symptoms in terminally ill children]
1Service d'hémato-oncologie pédiatrique, hôpital Sainte-Justine, 3175, chemin de la Côte-Sainte-Catherine, Montréal, QC, Canada, H3T 1C5. michel.duval@umontreal.ca
Insights
Palliative care for children is improving, but many still face severe symptoms. This review examines evidence for managing symptoms like fatigue and dyspnea, offering empirical approaches where data is lacking.
Area of Science:
- Pediatric Palliative Care
- Symptom Management in Children
Context:
- End-of-life care for children is advancing.
- Over half of dying children experience intractable symptoms.
- Clinical research on pediatric palliative care symptoms is limited.
Purpose:
- To review evidence on managing various symptoms in dying children.
- To provide empirical approaches for symptom management when evidence is scarce.
- To highlight the need for further clinical research in pediatric palliative care.
Summary:
- The review covers evidence for fatigue, anorexia, dyspnea, respiratory secretions, cough, constipation, dry mouth, urinary obstruction, terminal convulsions, and gasping.
- For symptoms lacking evidence-based data, an empiric approach is suggested.
- Short-acting benzodiazepines are noted as a simple, important treatment component.
Impact:
- Aims to improve the quality of life for dying children.
- Supports clinicians in managing complex end-of-life symptoms.
- Emphasizes the importance of comfort and relationships during a child's final days.
Abstract:
The care of children at the end of life is gradually improving. Nevertheless, more than half suffer from intractable symptoms before dying. Although pain has been the subject of clinical research, evidence-based data are almost completely lacking for other symptoms, highlighting the need for clinical research in palliative care. We review the available evidence on fatigue, anorexia, dyspnea, respiratory secretions, cough, constipation, mouth dryness, urinary obstruction, terminal convulsions and gasping. When evidence is lacking, we offer our empiric approach. Short duration benzodiazepines have become an important component of treatment that should remain simple, while providing the dying child the comfort needed to experience the highest quality relationships with those around him.
Related Concept Videos
Cancer Therapies
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Continuing Care
Methods of reducing fever
Pharmacological Methods of Reducing Fever:
Nursing Ethical Principles II
Consider the following scenario, which illustrates how these principles are applied in the care of Mr. John, a fifty-year-old teacher diagnosed with metastatic liver cancer.
Initially, Mr. John's cancer...
Tumor Immunotherapy
Chronic Pancreatitis II: Collaborative Care
Assessment:
