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[Systemic lupus erythematosus and herpes virus infection: three new observations]
H Bezanahary1, R Inaoui, V Allot
1Clinique médicale A, CHU Dupuytren, 2, avenue Martin-Luther-king, 87042 Limoges, France.
Abstract
Introduction:
Systemic lupus erythematosus is still of unknown origin. Viruses have long been postulated to play a role in its pathogenesis particularly cytomegalovirus and Epstein-Barr virus.
Exegese:
We describe three patients who presented acute onset of systémic lupus erythematosus concurrently with recent viral infection (two with cytomegalovirus and one with Epstein-Barr virus).
Conclusion:
The peculiar clinical events emphasize the difficulty of diagnosis at the onset of the disease and suggest possible role of these viruses in the pathogenesis of SLE.