Statistical evaluation and comparison of comet assay results
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Updated: Sep 28, 2026

07:57
A High-Throughput Comet Assay Approach for Assessing Cellular DNA Damage
Published on: May 10, 2022
Anna Ejchart1, Nina Sadlej-Sosnowska
1Drug Institute, 30/34 Chelmska Street, 00-725 Warsaw, Poland.
Mutation Research
|December 31, 2002
Abstract:
A method of critical evaluation of comet assay test results is proposed. This method is based on representing frequency histograms of tail moments and %DNA in the tail with the use of the unsymmetrical Weibull distribution. The distribution is fully characterized by two parameters: shape (alpha) and scale (beta). Coefficients of variation and confidence intervals of the parameters have been determined.

