Reproductive performance after hysteroscopic metroplasty in the hypoplastic uterus: a study of 29 cases

To evaluate the reproductive performance after hysteroscopic metroplasty performed for hypoplastic uterus.

Crossover study (15 patients) and descriptive analysis (14 patients).

Tertiary care university hospital.

Twenty-nine women (mean age: 31.4 years; range: 27-38.5 years) with a hypoplastic malformed uterus and a history of primary infertility and/or recurrent abortion and/or preterm delivery were included in this study. Fourteen women suffered from primary infertility and 15 women had previous pregnancies. Twenty-three women had been exposed to diethylstilboestrol in utero.

Women underwent hysteroscopic metroplasty between January 1996 and May 1999.

Rate of pregnancies and live births, anatomical results.

The mean follow up was 40 months (range: 13-67 months). Twenty-one women (72.4%) experienced 30 pregnancies. Thirteen women gave birth to 16 live infants. At the time of the follow up, four women were pregnant in the second trimester. Compared with previous pregnancies, the rate of deliveries increased from 3.8% to 63.2%. No complications occurred during metroplasty. The hysteroscopic anatomical results were good in all cases.

Our results suggest that hysteroscopic metroplasty, with its simplicity and minimal post-operative sequelae, seems to be an operation of choice in women with a hypoplastic malformed uterus and a history of severe infertility and/or recurrent pregnancy loss.