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Dynamics of Ly49 expressing cytotoxic lymphocyte subsets in response to virus infection
Craig D Peacock1, Weixin Xu, Susan E Stepp
1Department of Pathology, University of Massachusetts Medical Center, 55 Lake Avenue North, Worcester, MA 01655, USA.
Microbes and Infection
|December 31, 2002
Abstract:
Viral infections induce first a loss and then an increase in natural killer (NK) and CD8(+) T cells. NK cells expressing Ly49G2 were selectively expanded by several viruses and poly I:C. CD8(+) T cells expressing Ly49G2 were selectively expanded by poly I:C and participated in the antigen-specific response to lymphocytic choriomeningitis virus.