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Fe2+ decreases the taurine-induced Cl- current in acutely dissociated rat hippocampal neurons
Kuai Yu1, Shao-Yu Ge, Di-Yun Ruan
1School of Life Science, University of Science and Technology of China, Hefei Anhui, 230027 PR China.
Brain Research
|December 31, 2002
Abstract:
The effects of ferrous ions (Fe(2+)) on taurine-induced Cl(-) current (I(tau)) recorded from single neurons, which was freshly isolated from the rat hippocampal CA1 area, were studied with conventional whole-cell recording under voltage-clamp conditions. Using standard pharmacological approaches, we found that the currents gated by concentrations of taurine (
