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Updated: Sep 27, 2026

In Situ Detection and Single Cell Quantification of Metal Oxide Nanoparticles Using Nuclear Microprobe Analysis
Published on: February 3, 2018
Characterization of atmospheric particles by electron probe X-ray microanalysis
Bálint Alföldy1, Jorge Trincavelli, Szabina Török
1KFKI Atomic Energy Research Institute, Budapest, Hungary.
Abstract:
Microchemical glass standards were used to validate a quantitation method based on peak-to-background (P/B) ratios from electron probe x-ray microanalysis spectra. This standardless method was applied to the determination of concentrations of individual particles from Malpha or Lalpha lines, as well as from Kalpha lines. The algorithm was tested on particulate glass samples for diameters ranging from 1 to 20 microm. The determined concentrations did not depend on particle size. The certified values for elements were well matched, except for Na, which may migrate under electron bombardment. Finally, classification of qualitative results obtained for aerosol particles was completed by the P/B quantitative method.
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