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[LithoRisk: A software for calculating and visualising nephrolithiasis risk profiles]
M Marangella1, M Petrarulo, P G Daniele
1UOA Nefrologia Dialisi e Centro Calcolosi Renale, Ospedale Mauriziano Umberto I, Torino, Italy. mmarangella@mauriziano.it
Summary
LithoRisk software provides a clear graphical representation of urinary stone formation risk. This tool aids physicians in creating personalized treatment plans by analyzing urine chemistry and saturation levels.
Area of Science:
- Nephrology
- Biochemistry
- Medical Informatics
Context:
- Nephrolithiasis (kidney stone disease) pathogenesis involves urinary environment anomalies.
- Standard metabolic assessments require urine chemistry analysis and saturation calculations.
- Current patient reports are often fragmented, hindering effective therapeutic recommendations.
Purpose:
- Introduce LithoRisk, a dedicated software for graphical representation of kidney stone formation risk.
- To provide a user-friendly tool for visualizing saturation levels and diagnostic lithorisk profiles.
- To enhance medical management of nephrolithiasis through clear, comprehensive patient reports.
Summary:
- LithoRisk utilizes 24-hour urine chemistry values (e.g., calcium, oxalate, citrate) to calculate relative supersaturation (beta values).
- The software generates a graphical risk profile, displaying normal values in green and abnormal in red.
- It provides instantaneous calculation and reporting of beta values for common stone types like calcium oxalate, phosphate, uric acid, and cystine.
Impact:
- LithoRisk produces a unique, easy-to-understand report summarizing all relevant parameters for overall stone formation risk.
- Enables physicians to identify key abnormalities and establish individualized targets for reducing stone formation.
- Facilitates improved patient compliance and therapeutic outcomes in managing kidney stone disease.