The sella turcica in Nelson's syndrome

Abnormalities of the pituitary fossa were observed in 22 patients who were noted to have increased skin pigmentation after bilateral adrenalectomy for Cushing's syndrome. Radiographs of the skull revealed sella abnormalities in 13 of the 22 patients. In the remaining 9, hypocycloidal tomography demonstrated sella abnormalities. In 8 of these 9, localized bulging involved the anterior inferior wall of the sella turcica; in 1, the posterior inferior region was involved.