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Updated: Jul 30, 2026
08:53
Recurrent Escherichia coli Urinary Tract Infection Triggered by Gardnerella vaginalis Bladder Exposure in Mice
Published on: December 4, 2020
[Bacterial vaginosis and pregnancy]
1I Istituto di Clinica Ostetrica e Ginecologica, Cattedra di Ginecologia e Ostetricia, Università degli Studi di Roma La Sapienza, Roma, Italia.
La Clinica Terapeutica
|January 4, 2003
Summary
Bacterial vaginosis may contribute to premature rupture of membranes (PROM), a condition linked to about one-third of preterm births. This review explores the connection between bacterial vaginosis and PROM, highlighting risks to mother and baby.
Area of Science:
- Obstetrics and Gynecology
- Maternal-Fetal Medicine
- Microbiology
Context:
- Premature rupture of membranes (PROM) complicates 5-10% of pregnancies.
- PROM is a significant factor in approximately one-third of preterm births.
- PROM increases risks of perinatal and maternal morbidity and mortality.
Purpose:
- To review clinical and pathophysiologic evidence linking bacterial vaginosis (BV) to PROM.
- To explore the potential role of BV in preterm delivery.
Summary:
- Evidence suggests a link between bacterial vaginosis and the occurrence of PROM.
- Bacterial vaginosis may be a contributing factor in a significant number of preterm deliveries.
- Understanding this association is crucial for managing pregnancy complications.
Impact:
- Informing clinical practice regarding screening and management of BV in pregnant women.
- Potentially reducing rates of PROM and subsequent preterm birth.
- Improving maternal and neonatal outcomes by addressing a key risk factor.
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