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Related Experiment Videos

Miniature cylindrical ion trap mass spectrometer.

Garth E Patterson1, Andrew J Guymon, Leah S Riter

  • 1Chemistry Department, Purdue University, West Lafayette, Indiana 47907-1393, USA.

Analytical Chemistry
|January 4, 2003
PubMed
Summary

A new miniature, battery-operated ion trap mass spectrometer offers laboratory-level performance in a portable format. This device supports tandem mass spectrometry and achieves a mass range of 250 Th.

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Area of Science:

  • Analytical Chemistry
  • Instrument Development
  • Mass Spectrometry

Background:

  • Laboratory-scale mass spectrometers offer high performance but lack portability.
  • Miniaturization of analytical instruments is crucial for field applications.
  • Cylindrical ion trap mass spectrometers are known for their versatility.

Purpose of the Study:

  • To describe a novel miniature cylindrical ion trap mass spectrometer.
  • To present preliminary performance data of the portable instrument.
  • To demonstrate the feasibility of battery-operated mass spectrometry.

Main Methods:

  • Development of a compact, battery-operated cylindrical ion trap mass spectrometer.
  • Custom design of electronic components including RF scanning, data acquisition, and lens power supplies.

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  • Implementation of direct leak and membrane inlet systems for sample introduction.
  • Development of a custom software application for instrument control and data analysis.

    • Main Results:

    • The miniature mass spectrometer maintains functionality and performance comparable to laboratory-scale instruments.
    • The instrument is capable of performing tandem mass spectrometry experiments.
    • A mass/charge range of approximately 250 Th with unit mass resolution was demonstrated.
    • Custom electronic components and software were successfully integrated.

    Conclusions:

    • A functional miniature cylindrical ion trap mass spectrometer has been developed.
    • The portable instrument demonstrates promising performance for various analytical applications.
    • Battery operation and miniaturization do not significantly compromise mass spectrometry capabilities.