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Marriage of XAFS and crystallography for structure-function studies of metalloproteins
S Samar Hasnain1, Richard W Strange
1College of Biology and Medicine, CLRC Daresbury Laboratory, Warrington WA4 4AD, UK. s.hasnain@dl.ac.uk
Journal of Synchrotron Radiation
|January 4, 2003
Abstract:
Metalloproteins constitute a significant proportion of all known genomes. In this Article it is shown that the marriage of two synchrotron-radiation-based structural techniques, namely high-resolution crystallography and XAFS, can yield unprecedented levels of structural information that is directly relevant to the mechanism/function of these important macromolecules.