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Eukaryotic cells and microbial pathogens: a familiar couple take centre stage
Craig R Roy1, F Gisou van der Goot
1Yale University School of Medicine, Boyer Centre for Molecular Medicine, Section of Microbial Pathogenesis, 295 Congress Avenue, New Haven, CT 06536-0812, USA. craig.roy@yale.edu
Abstract:
The interaction of a microbial pathogen with its host is a highly dynamic process shaped by evolution. Understanding cellular responses to microbial products is essential for a complete understanding of virulence. Similarly, studies aimed at determining how a particular virulence factor functions have helped unravel molecular mechanisms that govern eukaryotic cellular events. These two seemingly diverse areas were brought together on the beautiful Spanish Costa Brava in a recent meeting (October 13-17, 2002) sponsored by European Research Conferences (EURESCO) and the European Molecular Biology Organization (EMBO).