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Updated: Sep 27, 2026

Mouse Kidney Transplantation: Models of Allograft Rejection
Published on: October 11, 2014
[Immunological factors for chronic rejection and the methods for the prevention of chronic allograft nephropathy]
1Department of Urology, Osaka University Graduate School of Medicine.
For the prevention of the immunological chronic rejection, HLA-DRB1 allele matching, enough immunosuppression in the induction phase and pathological diagnosis by non-episode and protocol biopsy are the effective methods. For the prevention of the non-immunological chronic rejection, treatments for hypertension, hyperlipidemia and hyperfiltration are the effective treatments.
For the prevention of the immunological chronic rejection, HLA-DRB1 allele matching, enough immunosuppression in the induction phase and pathological diagnosis by non-episode and protocol biopsy are the effective methods. For the prevention of the non-immunological chronic rejection, treatments for hypertension, hyperlipidemia and hyperfiltration are the effective treatments.
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