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Model of elastic responses of single DNA molecules in collapsing transition
Hirofumi Wada1, Yoshihiro Murayama, Masaki Sano
1Department of Physics, University of Tokyo, Hongo, Tokyo 113-0033, Japan. wada@daisy.phys.s.u-tokyo.ac.jp
Abstract:
We present a simple phenomenological model to describe elastic responses of a collapsed single DNA molecule. The model is represented by the elastic theory for the wormlike chain combined with the order-parameter equation, which accounts for the intramolecular transition kinetics. Our continuum and discrete model reproduces the force plateaus and the stick-release patterns in the force-extension curves, respectively. Both of the elastic responses have been observed experimentally by changing the concentration of the condensing agents.