Related Experiment Videos
[Analysis of serologic typing error for HLA-A and HLA-B in Chinese]
Yu-Dong Dai1, Qi-Jun Sun, Yi-Hong Zhang
1Nanjing Red Cross Blood Center, Nanjing 210008, China.
Zhongguo Shi Yan Xue Ye Xue Za Zhi
|January 7, 2003
Abstract:
Serological mistypings of HLA-A and HLA-B in 27 cases were analyzed. The results showed that for HLA-A and HLA-B typing, the rates of incorrect antigen assignments were significantly higher than rates of antigen misses (P < 0.05), but there was no significant difference between HLA-A and HLA-B typings. The frequencies of miss-assigned HLA-A and HLA-B specificities were A1 (66.7%), A3 (50.0%), A11 (13.5%), A9 (11.8%), A19 (7.1%), and B16 (50.0%), B48 (43.9%), B15 (16.7%), B40 (11.1%), B13 (10.0%) and B17 (9.1%). In conclusion, the serologic and DNA-based typing techniques should be reciprocally complementary in HLA-A and HLA-B typing.