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Updated: Sep 27, 2026

Application of DNA Fingerprinting using the D1S80 Locus in Lab Classes
Published on: July 17, 2021
[Distribution of D1S80 alleles in a random sample of the population of the Russian Federation]
Abstract:
The distribution of alleles of chromosomal locus D1S80 was studied within a random selection of population of the Russian Federation. Typing was made for 255 persons who were not blood relatives and who lived in 56 Russia's regions. A correlation was found between the observed frequencies of genotypes and those theoretically expected and estimated on the basis of the hypothesis of Hardy-Weinberg equilibrium. The main population characteristics of locus D1S80, i.e. probability of an incidental coincidence of a genotype, discriminating potential, polymorphism factor, potential excluding cases of incorrectly named parents and mean value of paternity index, were estimated to evaluate the efficiency of the locus as a molecular-genetic marker in solving the identification tasks applicable to Russia's population. The obtained descriptive data on the distribution of alleles of the studied locus in Russia's population can be used to determine the needed estimated parameters in interpreting the results of forensic molecular-genetic identification examinations.
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