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Related Experiment Videos

[Use of hypertonic solutions through umbilical cord vessels].

J Mücke, C Vogtmann

    Zentralblatt Fur Gynakologie
    |January 1, 1976
    PubMed
    Summary
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    Sodium bicarbonate (NaHCO3) administered via the umbilical cord in newborns can lead to skin necrosis and fibularis paresis. Umbilical vein puncture or cannulation is preferred over catheterization for effective buffer therapy when indicated.

    Area of Science:

    • Neonatal Medicine
    • Pediatric Pharmacology
    • Clinical Therapeutics

    Context:

    • Postnatal administration of sodium bicarbonate (NaHCO3) via the umbilical cord in newborns.
    • Complications observed include skin necroses and fibularis paresis.
    • Discussion of challenges in postnatal buffer therapy.

    Purpose:

    • To report a case of adverse effects following umbilical NaHCO3 administration.
    • To discuss the problems and preferred methods of postnatal buffer therapy.
    • To evaluate different umbilical vein access techniques for therapy.

    Summary:

    • A newborn developed skin necrosis and fibularis paresis after receiving NaHCO3 through the umbilical cord.
    • The study reviews the advantages and disadvantages of umbilical vein puncture/cannulation versus catheterization.

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  • Umbilical vein puncture or cannulation is recommended for effective buffer therapy under strict indications.
  • Impact:

    • Highlights potential risks associated with umbilical NaHCO3 administration in neonates.
    • Informs clinical practice regarding safe and effective umbilical vein access for neonatal resuscitation and therapy.
    • Emphasizes the importance of adhering to strict indications for buffer therapy to prevent adverse events.