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Thymidine-dependent small-colony variants of Staphylococcus aureus exhibit gross morphological and ultrastructural
Barbara C Kahl1, Gunnar Belling, Rudolf Reichelt
1Institute of Medical Microbiology, University of Muenster Hospital and Clinics, Muenster, Germany. kahl@uni-muenster.de
Journal of Clinical Microbiology
|January 9, 2003
Abstract:
Thymidine-dependent small-colony variants (SCV) of Staphylococcus aureus exhibited unusual colony morphology with "fried-egg" or pinpoint white colonies on agar plates and pleomorphic cocci as determined by Gram staining. Electron microscopy revealed enlarged cocci with incomplete or multiple cross walls consistent with impaired cell separation. Fried-egg SCV phenotypes could be reversed by thymidine supplementation.