Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A supercritical fluid-based coating technology. 2: solubility considerations.

I Ribeiro Dos Santos1, C Thies, J Richard

  • 1Unité de Vectorisation Particulaire INSERM - ERIT M 0104, 10 rue A Boquel, 49100 Angers, France.

Journal of Microencapsulation
|January 10, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Various lipid anchors on amphiphilic polyoxazolines to reach efficient intracellular delivery.

International journal of pharmaceutics·2023
Same author

Low-dose ketamine infusion for post-cesarean delivery analgesia in patients with opioid use disorder.

International journal of obstetric anesthesia·2021
Same author

Author Correction: Nearly all the sky is covered by Lyman-α emission around high-redshift galaxies.

Nature·2018
Same author

Nearly all the sky is covered by Lyman-α emission around high-redshift galaxies.

Nature·2018
Same author

Evaluation of New Antibacterial Drugs and their Combinations in a Murine Model to Identify Short Duration Alternative Chemotherapy for Leprosy.

Indian journal of leprosy·2018
Same author

Breast magnetic resonance imaging: are those who need it getting it?

Current oncology (Toronto, Ont.)·2017
Same journal

Rationally engineered essential oil-loaded nanocarriers for acne vulgaris: integrating multiscale molecular modeling, machine learning, and response surface optimization.

Journal of microencapsulation·2026
Same journal

Retinyl palmitate-loaded nanostructured lipid carriers prepared by the phase inversion temperature method: Physicochemical properties, <i>in vitro</i> skin permeation, and occlusion ability.

Journal of microencapsulation·2026
Same journal

Green synthesis of silver nanoparticles using <i>Swertia chirayita</i> and their antioxidant and anticancer potential.

Journal of microencapsulation·2026
Same journal

Management of coronary artery disease via simvastatin-loaded novasomes.

Journal of microencapsulation·2026
Same journal

Phyto-engineered CuO nanoparticles from gum <i>Eucalyptus camaldulensis</i>: a GC-MS, molecular docking, and bioactivity study.

Journal of microencapsulation·2026
Same journal

Development and optimization of gallic acid-enriched nanostructured lipid carriers for the amelioration of rheumatic inflammation: <i>in-vitro</i> and <i>in-vivo</i> study.

Journal of microencapsulation·2026
See all related articles

This study measured the solubility of coating materials in supercritical carbon dioxide (SC CO2) to enable a solvent-free coating process. Mixtures selectively extracted lower melting point components, aiding material selection.

Area of Science:

  • Materials Science
  • Chemical Engineering
  • Physical Chemistry

Background:

  • Developing solvent-free coating processes is crucial for environmental sustainability and reduced manufacturing costs.
  • Supercritical carbon dioxide (SC CO2) offers a tunable and environmentally benign solvent alternative for various applications.
  • Selection of appropriate coating materials is essential for the successful implementation of SC CO2-based coating technologies.

Purpose of the Study:

  • To evaluate the solubility of various lipidic compounds in SC CO2.
  • To identify suitable coating materials for a previously described solvent-free coating process.
  • To understand the selective extraction behavior of mixed-component materials in SC CO2.

Main Methods:

  • Solubility measurements of waxes, triglycerides, and glyceride mixtures were conducted in SC CO2 using a static method.

Related Experiment Videos

  • Experiments covered a temperature range of 13-52°C and pressures from 50-220 bar.
  • Thermal analysis was used to characterize the soluble and insoluble fractions of the coating materials.

    • Main Results:

    • Solubility of tested lipidic compounds in SC CO2 was quantified under varying temperature and pressure conditions.
    • Mixed-component materials, such as Gelucire, demonstrated selective extraction of lower melting point constituents.
    • The solubility and extraction behavior were dependent on the specific chemical nature and physical state of the CO2.

    Conclusions:

    • Solubility data in SC CO2 provides a basis for selecting effective coating materials.
    • Selective extraction from mixed lipidic compounds is achievable using SC CO2, enabling tailored material processing.
    • This research supports the development of environmentally friendly, solvent-free coating applications.