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The EMBL Nucleotide Sequence Database: major new developments.

Guenter Stoesser1, Wendy Baker, Alexandra van den Broek

  • 1EMBL Outstation, The European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK. stoesser@ebi.ac.uk

Nucleic Acids Research
|January 10, 2003
PubMed
Summary
This summary is machine-generated.

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The EMBL Nucleotide Sequence Database provides access to public nucleotide sequences, updated quarterly. It collaborates internationally and offers various tools for data retrieval and analysis.

Area of Science:

  • Bioinformatics
  • Genomics
  • Molecular Biology

Background:

  • The EMBL Nucleotide Sequence Database is a key resource for public nucleotide sequences.
  • It is maintained by the European Bioinformatics Institute (EBI) in collaboration with DDBJ and GenBank.

Purpose of the Study:

  • To describe the EMBL Nucleotide Sequence Database's resources and services.
  • To highlight its role in data sharing and accessibility for researchers.

Main Methods:

  • Data incorporation through Webin and automated procedures from large-scale centers and patent offices.
  • Daily data exchange with international collaborators (DDBJ, GenBank) for synchronization.
  • Quarterly database releases and network services (FTP, Email, WWW) for data access.

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Main Results:

  • The database integrates, organizes, and distributes nucleotide sequences from public sources.
  • It provides access to up-to-date data through various network services.
  • The Sequence Retrieval System (SRS) integrates multiple molecular biology databases.
  • Tools like Fasta and BLAST are available for sequence similarity searching.

Conclusions:

  • The EMBL Nucleotide Sequence Database is a comprehensive and accessible resource for nucleotide sequences.
  • International collaboration ensures data synchronization and optimal resource availability.
  • Advanced search tools facilitate sequence comparison and analysis for researchers worldwide.