The GENETPIG database: a tool for comparative mapping in pig (Sus scrofa).

Area of Science:

• Genomics
• Animal Genetics
• Bioinformatics

Background:

• The European GENETPIG project aimed to identify genes controlling economic traits in pigs.
• Gene mapping is crucial for understanding genetic contributions to economically important traits in livestock.
• Dissemination of genetic and mapping data is essential for scientific progress.

Purpose of the Study:

• To establish a centralized database for storing and disseminating results from the GENETPIG project.
• To facilitate access to mapped porcine and human ESTs (expressed sequence tags) on the pig genome.
• To link mapping data with other genomic resources and provide functional annotations.

Main Methods:

• Mapping of approximately 630 porcine and human ESTs onto the pig genome.
• Collection and integration of mapping results within the GENETPIG database.
• Linking EST mapping data with existing pig genome maps and comparative mapping information.
• Functional annotation of mapped ESTs based on significant similarity to known genes.

Main Results:

• The GENETPIG database now contains mapping data for 630 ESTs.
• The database integrates diverse mapping information, including comparative genomics.
• Functional annotations are provided for ESTs with established gene similarities.
• The database is publicly accessible via the internet.

Conclusions:

• The GENETPIG database serves as a valuable resource for pig genetics research.
• It enhances the understanding of genes controlling economic traits in pigs.
• Facilitates comparative genomics studies between pigs and other species.
• Promotes further research in animal genetics and breeding through data accessibility.