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Related Experiment Videos

MGD: the Mouse Genome Database.

Judith A Blake1, Joel E Richardson, Carol J Bult

  • 1The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA. jblake@informatics.jax.org

Nucleic Acids Research
|January 10, 2003
PubMed
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The Mouse Genome Database (MGD) provides an integrated resource for mouse genetics, linking genotype to phenotype information. It aids in understanding human biology and interpreting the human genome using the mouse model organism.

Area of Science:

  • Genomics
  • Bioinformatics
  • Comparative Genomics

Background:

  • The laboratory mouse is a key model organism for human genome interpretation and understanding human biology.
  • Community databases are essential for integrating biological information.
  • Existing resources require comprehensive integration of experimental and genomic data.

Purpose of the Study:

  • To present an integrated information resource for the laboratory mouse.
  • To provide detailed genotype-to-phenotype information.
  • To facilitate the interpretation of the human genome and human biology through mouse data.

Main Methods:

  • Curating experimental details from literature and online genomic data sources.
  • Integrating information on genes, gene products, sequences, and phenotypes.

Related Experiment Videos

  • Implementing database structures for controlled vocabularies and phenotype classification systems.

    • Main Results:

    • The Mouse Genome Database (MGD) offers an extensively integrated resource.
    • Detailed genotype (sequence) to phenotype information is curated and presented.
    • Collaborative efforts enhance the definitive dataset for the laboratory mouse.

    Conclusions:

    • MGD serves as a vital community resource for mouse genetics research.
    • The integration of controlled vocabularies and phenotype classification enhances data usability.
    • MGD significantly contributes to understanding gene function and human biology.